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1

The control of diastereoselectivity in the Michael reaction of ketonic enolates with crotonic acid derivatives

E.J. Corey, Ioannis N. Houpis

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 244 KB

english, 1993

2

Synthesis of PPAR Agonist via Asymmetric Hydrogenation of a Cinnamic Acid Derivative and Stereospecific Displacement of ( S )-2-Chloropropionic Acid

Houpis, Ioannis N., Patterson, Lawrence E., Alt, Charles A., Rizzo, John R., Zhang, Tony Y., Haurez, Michael

Journal:

Organic Letters

Year:

2005

Language:

english

File:

PDF, 114 KB

english, 2005

3

Nickel catalyzed addition of organozincates to optically pure vinylic sulfoxides. Synthesis of the phosphodiesterase IV inhibitor L-765,527 (CDP-840)

Ioannis N. Houpis, Audrey Molina, Ilias Dorziotis, Robert A. Reamer, R.P. Volante, Paul J. Reider

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 204 KB

english, 1997

4

Olefin synthesis by the Pd-catalyzed cross coupling on sulfonylhydrazones with aromatic sulfinates

Tan, Hongyu, Houpis, Ioannis, Li, Yunfei, Wang, Youchu, Liu, Renmao, Chen, Zhilong

Journal:

Tetrahedron Letters

Year:

2016

Language:

english

File:

PDF, 2.60 MB

english, 2016

5

Ni-catalyzed nucleophilic conjugate additions of Grignard and organozincate reagents to substituted 4-vinylpyridines. General synthesis of phosphodiesterase IV inhibitors

Ioannis N. Houpis, Jaemoon Lee, Ilias Dorziotis, Audrey Molina, Bob Reamer, R.P. Volante, Paul J. Reider

Journal:

Year:

1998

Language:

english

File:

PDF, 614 KB

english, 1998

6

Total synthesis of glycinoeclepin A

Corey, E. J., Houpis, Ioannis N.

Journal:

Journal of the American Chemical Society

Year:

1990

Language:

english

File:

PDF, 293 KB

english, 1990

7

ChemInform Abstract: Olefin Preparation via Palladium-Catalyzed Oxidative De-Azotative and De-Sulfitative Internal Cross-Coupling of Sulfonylhydrazones.

Tan, Hongyu, Houpis, Ioannis, Liu, Renmao, Wang, Youchu, Chen, Zhilong

Journal:

Year:

2015

File:

PDF, 23 KB

2015

8

ChemInform Abstract: Amination of Aryl Halides Using Copper Catalysis.

Fengrui Lang, Daniel Zewge, Ioannis N. Houpis, R. P. Volante

Journal:

Year:

2001

File:

PDF, 32 KB

2001

9

Synthesis of a Muscarinic Receptor Antagonist via a Diastereoselective Michael Reaction, Selective Deoxyfluorination and Aromatic Metal−Halogen Exchange Reaction

Mase, Toshiaki, Houpis, Ioannis N., Akao, Atsushi, Dorziotis, Ilias, Emerson, Khateeta, Hoang, Thoa, Iida, Takehiko, Itoh, Takahiro, Kamei, Keisuke, Kato, Shinji, Kato, Yoshiaki, Kawasaki, Masashi, La

Journal:

Journal of Organic Chemistry

Year:

2001

Language:

english

File:

PDF, 157 KB

english, 2001

10

ChemInform Abstract: Olefin Synthesis by the Pd-Catalyzed Cross Coupling on Sulfonylhydrazones with Aromatic Sulfinates.

Tan, Hongyu, Houpis, Ioannis, Li, Yunfei, Wang, Youchu, Liu, Renmao, Chen, Zhilong

Journal:

Year:

2016

File:

PDF, 23 KB

2016

11

ChemInform Abstract: Nickel Catalyzed Reactions of Nucleophiles with Unactivated and Partially Activated Olefins and Acetylenes

Ioannis N. Houpis, Jaemoon Lee

Journal:

Year:

2000

File:

PDF, 25 KB

2000

12

Synthesis of functionalized furo[2,3-b]pyridines via the Pd-catalyzed coupling of acetylenes to iodopyridones. Preparation of a key intermediate to a new HIV protease inhibitor L-754,394

Ioannis N. Houpis, W.B. Choi, P.J. Reider, Audrey Molina, Hywyn Churchill, Joseph Lynch, R.P. Volante

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 301 KB

english, 1994

13

Parathyroid hormone–related peptide (PTHrP), parathyroid hormone/parathyroid hormone–related peptide receptor 1 (PTHR1), and MSX1 protein are expressed in central and peripheral giant cell granulomas of the jaws

Constantinos H. Houpis, Konstantinos I. Tosios, Dimitrios Papavasileiou, Panagiotis G. Christopoulos, Ioannis G. Koutlas, Alexandra Sklavounou, Constantinos Alexandridis

Journal:

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology

Year:

2010

Language:

english

File:

PDF, 2.82 MB

english, 2010

14

Palladium- and Copper-Catalyzed Site Selective Monoamination of Dibromobenzoic Acid

Ioannis N. Houpis, Koen Weerts, Ulrike Nettekoven, Martine Canters, Hongyu Tan, Renmao Liu, Youchu Wang

Journal:

Advanced Synthesis & Catalysis

Year:

2011

Language:

english

File:

PDF, 237 KB

english, 2011

15

Condensation of 2-methylbenzoxazole with aromatic aldehydes bearing acidic protons. A convenient coupling in the synthesis of the HIV-reverse transcriptase inhibitor L-696,229

Houpis, Ioannis N., Molina, Audrey, Lynch, Joseph, Reamer, Robert A., Volante, R. P., Reider, Paul J.

Journal:

Journal of Organic Chemistry

Year:

1993

Language:

english

File:

PDF, 346 KB

english, 1993

16

Regioselective Cross-Coupling Reactions of Boronic Acids with Dihalo Heterocycles

Houpis, Ioannis N., Liu, Renmao, Wu, Yanfei, Yuan, Yukuan, Wang, Youchu, Nettekoven, Ulrike

Journal:

Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 774 KB

english, 2010

17

ChemInform Abstract: Palladium-Catalyzed Coupling of Sulfonylhydrazones with Heteroaromatic 2-Amino-halides (Barluenga Reaction): Exploring the Electronics of the Sulfonylhydrazone.

Tan, Hongyu, Houpis, Ioannis, Liu, Renmao, Wang, Youchu, Chen, Zhilong, Fleming, Matthew J.

Journal:

Year:

2015

File:

PDF, 22 KB

2015

18

Stereoselective C-Glycosylation Reactions with Arylzinc Reagents

Lemaire, Sébastien, Houpis, Ioannis N., Xiao, Tingting, Li, Juanjuan, Digard, Eric, Gozlan, Charlotte, Liu, Renmao, Gavryushin, Andrey, Diène, Coura, Wang, Youchu, Farina, Vittorio, Knochel, Paul

Journal:

Organic Letters

Year:

2012

Language:

english

File:

PDF, 384 KB

english, 2012

19

Synthesis of (4′R)-Azido-(2′R)-2′-Deoxy-2′-C-Methyluridine and Its Esters by Direct Iodide Displacement

Benhaim, Cyril, Lemaire, Sébastien, Gaekens, Tim, Govaerts, Tom, Houpis, Ioannis, Reniers, Peter, Van Looy, Anja, Vermeulen, Wim, Bernhardt, Sebastian, Diène, Coura, Knochel, Paul, Farina, Vittorio

Journal:

Year:

2013

Language:

english

File:

PDF, 190 KB

english, 2013

20

The Palladium Catalyzed Coupling of β-Trifuoromethanesulfonyl α,β-Unsaturated Esters and Ketones with β-Stannyl Enoates: Synthesis of Electron Deficient Dienes

Houpis, Ioannis N., DiMichele, Lisa, Molina, Audrey

Journal:

Year:

1993

File:

PDF, 159 KB

1993

21

Synthesis of 4,4′-Disubstituted Azepines via Ring-Closing Metathesis Reaction and Asymmetric Arylation of Lactones

Delhaye, Laurent, Merschaert, Alain, Diker, Khalid, Houpis, Ioannis

Journal:

Year:

2006

Language:

english

File:

PDF, 113 KB

english, 2006

22

Useful new annulation reactions of vicinal dicarboxylic esters

E.J. Corey, Wei-guo Su, Ioannis N. Houpis

Journal:

Tetrahedron Letters

Year:

1986

Language:

english

File:

PDF, 221 KB

english, 1986

23

Carboxylate Directed Cross-Coupling Reactions in the Synthesis of Trisubstituted Benzoic Acids

Houpis, Ioannis N., Huang, Changkang, Nettekoven, Ulrike, Chen, Jason G., Liu, Renmao, Canters, Martine

Journal:

Organic Letters

Year:

2008

Language:

english

File:

PDF, 104 KB

english, 2008

24

Nickel Catalyzed Reactions of Nucleophiles with Unactivated and Partially Activated Olefins and Acetylenes

Ioannis N. Houpis, Jaemoon Lee

Journal:

Year:

2000

Language:

english

File:

PDF, 920 KB

english, 2000

25

Palladium(II)-catalyzed coupling of 2-carboxyethyl enol triflates with organostannanes.

Ioannis N. Houpis

Journal:

Tetrahedron Letters

Year:

1991

Language:

english

File:

PDF, 257 KB

english, 1991

26

Metal-halogen exchange-initiated cyclization of iodo carbonyl compounds

Manning P. Cooke Jr., Ioannis N. Houpis

Journal:

Tetrahedron Letters

Year:

1985

Language:

english

File:

PDF, 240 KB

english, 1985

27

Amination of aryl halides using copper catalysis

Fengrui Lang, Daniel Zewge, Ioannis N Houpis, R.P Volante

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 58 KB

english, 2001

28

Utilization of Sequential Palladium-Catalyzed Cross-Coupling Reactions in the Stereospecific Synthesis of Trisubstituted Olefins

Houpis, Ioannis N., Shilds, Didier, Nettekoven, Ulrike, Schnyder, Anita, Bappert, Erhart, Weerts, Koen, Canters, Martine, Vermuelen, Wim

Journal:

Organic Process Research & Development

Year:

2009

Language:

english

File:

PDF, 578 KB

english, 2009

29

A practical synthesis of the 5-chloromethyl-furo[2,3-b]pyridine pharmacophore

Woo-Baeg Choi, Ioannis N Houpis, Hywyn R.O Churchill, Audrey Molina, Joseph E Lynch, R.P Volante, Paul J Reider, Anthony O King

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 252 KB

english, 1995

30

Towards the synthesis of HIV-protease inhibitors. Synthesis optically pure 3-carboxyl-decahydroisoquinolines.

Ioannis N. Houpis, Audrey Molina, Robert A. Reamer, Joseph E. Lynch, R.P. Volante, Paul J. Reider

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 242 KB

english, 1993

31

ChemInform Abstract: Regioselective Cross-Coupling Reactions of Boronic Acids with Dihalo Heterocycles.

Ioannis N. Houpis, Renmao Liu, Yanfei Wu, Yukuan Yuan, Youchu Wang, Ulrike Nettekoven

Journal:

Year:

2011

File:

PDF, 35 KB

2011

32

Regiochemistry of the metal-halogen exchange induced cyclization of ω-iodoepoxides

Manning P. Cooke Jr., Ioannis N. Houpis

Journal:

Tetrahedron Letters

Year:

1985

Language:

english

File:

PDF, 225 KB

english, 1985

33

Synthesis of (1R,2S)-1-Amino-2-vinylcyclopropanecarboxylic Acid Vinyl-ACCA) Derivatives: Key Intermediates for the Preparation of Inhibitors of the Hepatitis C Virus NS3 Protease

Beaulieu, Pierre L., Gillard, James, Bailey, Murray D., Boucher, Colette, Duceppe, Jean-Simon, Simoneau, Bruno, Wang, Xiao-Jun, Zhang, Li, Grozinger, Karl, Houpis, Ioannis

Journal:

Journal of Organic Chemistry

Year:

2005

Language:

english

File:

PDF, 245 KB

english, 2005

34

Copper-Catalyzed C–N Coupling in the Synthesis of Integrase Inhibitors of Immunodeficiency Viruses

Lin, Jinguan, Houpis, Ioannis N., Liu, Renmao, Wang, Youchu, Zhang, Jianqian

Journal:

Organic Process Research & Development

Year:

2014

Language:

english

File:

PDF, 781 KB

english, 2014

35

Practical Synthesis of (2′ R )-2′-Deoxy-2′- C -methyluridine by Highly Diastereoselective Homogeneous Hydrogenation

Lemaire, Sébastien, Houpis, Ioannis, Wechselberger, Rainer, Langens, Jaak, Vermeulen, Wim A. A., Smets, Nico, Nettekoven, Ulrike, Wang, Youchu, Xiao, Tingting, Qu, Haisheng, Liu, Renmao, Jonckers, Ti

Journal:

Journal of Organic Chemistry

Year:

2011

Language:

english

File:

PDF, 740 KB

english, 2011

36

Synthesis of the orally active spiroindoline-based growth hormone secretagogue, MK-677

Peter E. Maligres, Ioannis Houpis, Kai Rossen, Audrey Molina, Jess Sager, Veena Upadhyay, Kenneth M. Wells, Robert A. Reamer, Joseph E. Lynch, David Askin, R.P. Volante, Paul J. Reider, Peter Houghton

Journal:

Year:

1997

Language:

english

File:

PDF, 706 KB

english, 1997

37

Total synthesis of (.+-.)-ginkgolide B

Corey, Elias J., Kang, Myung Chol., Desai, Manoj C., Ghosh, Arun K., Houpis, Ioannis N.

Journal:

Journal of the American Chemical Society

Year:

1988

Language:

english

File:

PDF, 453 KB

english, 1988

38

Synthesis of a new generation reverse transcriptase inhibitor via the BCl3/GaCl3-induced condensation of anilines with nitriles (sugasawa reaction)

Ioannis N. Houpis, Audrey Molina, Alan W. Douglas, Lyndon Xavier, Joseph Lynch, R.P. Volante, P.J. Reider

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 270 KB

english, 1994

39

New Synthesis of 2′,4′-Functionalized Nucleotides via Stereospecific Hydrogenation and Azidation Reactions

Houpis, Ioannis, Lemaire, Sebastien, Farina, Vittorio, Xiao, Tingting, Liu, Renmao, Nettekoven, Ulrike, Wang, Youchu

Journal:

Year:

2012

Language:

english

File:

PDF, 191 KB

english, 2012

40

Olefin Preparation via Palladium-Catalyzed Oxidative De-Azotative and De-Sulfitative Internal Cross-Coupling of Sulfonylhydrazones

Tan, Hongyu, Houpis, Ioannis, Liu, Renmao, Wang, Youchu, Chen, Zhilong

Journal:

Organic Letters

Year:

2015

Language:

english

File:

PDF, 752 KB

english, 2015

41

Synthesis of a Muscarinic Receptor Antagonist via a Diastereoselective Michael Reaction, Selective Deoxyfluorination and Aromatic Metal-Halogen Exchange Reaction.

Mase, Toshiaki, Houpis, Ioannis N., Akao, Atsushi, Dorziotis, Ilias, Emerson, Khateeta, Hoang, Thoa, Iida, Takehiko, Itoh, Takahiro, Kamei, Keisuke, Kato, Shinji, Kawasaki, Masashi, Lang, Fengrui, Lee

Journal:

Journal of Organic Chemistry

Year:

2002

Language:

english

File:

PDF, 7 KB

english, 2002

42

Efficient Synthesis of ( S )-2-(Cyclopentyloxycarbonyl)-amino-8-nonenoic Acid: Key Building Block for BILN 2061, an HCV NS3 Protease Inhibitor

Wang, Xiao-jun, Zhang, Li, Smith-Keenan, Lana L., Houpis, Ioannis N., Farina, Vittorio

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 62 KB

english, 2007

43

Utilization of Sequential Palladium-Catalyzed Cross-Coupling Reactions in the Stereospecific Synthesis of Trisubstituted Olefins

Houpis, Ioannis N., Schils, Didier, Nettekoven, Ulrike, Schnyder, Anita, Bappert, Erhart, Weerts, Koen, Canters, Martine, Vermeulen, Wim A. A.

Journal:

Organic Process Research & Development

Year:

2009

File:

PDF, 28 KB

2009

44

Efficient Large-Scale Synthesis of BILN 2061, a Potent HCV Protease Inhibitor, by a Convergent Approach Based on Ring-Closing Metathesis

Yee, Nathan K., Farina, Vittorio, Houpis, Ioannis N., Haddad, Nizar, Frutos, Rogelio P., Gallou, Fabrice, Wang, Xiao-jun, Wei, Xudong, Simpson, Robert D., Feng, Xuwu, Fuchs, Victor, Xu, Yibo, Tan, Jon

Journal:

Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 248 KB

english, 2006

45

Synthesis of a Long Acting HIV Protease Inhibitor via Metal or Enzymatic Reduction of the Appropriate Chloro Ketone and Selective Zinc Enolate Condensation with an Amino Epoxide

Houpis, Ioannis N., Liu, Renmao, Liu, Lin, Wang, Yanfei, Dong, Nengfa, Zhao, Xiangan, Zhang, Yan, Xiao, Tingting, Wang, Youchu, Depre, Dominique, Nettekoven, Ulrike, Vogel, Michael, Wilson, Rob, Colli

Journal:

Advanced Synthesis & Catalysis

Year:

2013

Language:

english

File:

PDF, 310 KB

english, 2013

46

Carboxylate-Directed Kumada Coupling of an Acetaldehyde Synthon with 2-Bromobenzoates Used towards the Synthesis of Isochromanes

Houpis, Ioannis, Van Hoeck, Jean-Pierre, Tilstam, Ulf

Journal:

Year:

2007

Language:

english

File:

PDF, 91 KB

english, 2007

47

Palladium-Catalyzed Coupling of Sulfonylhydrazones with Heteroaromatic 2-Amino-Halides (Barluenga Reaction): Exploring the Electronics of the Sulfonylhydrazone

Tan, Hongyu, Houpis, Ioannis, Liu, Renmao, Wang, Youchu, Chen, Zhilong, Fleming, Matthew J.

Journal:

Organic Process Research & Development

Year:

2015

Language:

english

File:

PDF, 539 KB

english, 2015

48

Practical Synthesis of 2-(2-Isopropylaminothiazol-4-yl)-7-methoxy-1 H -quinolin-4-one: Key Intermediate for the Synthesis of Potent HCV NS3 Protease Inhibitor BILN 2061

Frutos, Rogelio, Haddad, Nizar, Houpis, Ioannis, Johnson, Michael, Smith-Keenan, Lana, Fuchs, Victor, Yee, Nathan, Farina, Vittorio, Faucher, Anne-Marie, Brochu, Christian, Haché, Bruno, Duceppe, Jean

Journal:

Year:

2006

Language:

english

File:

PDF, 121 KB

english, 2006

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